Predictive factors of weaning from mechanical ventilation and extubation outcome: A systematic review
Highlight: Forty-three articles (7929 patients) were analyzed, presenting 56 different parameters related to weaning/extubation outcome.
Ciência aplicada
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Produção científica
Highlight: Forty-three articles (7929 patients) were analyzed, presenting 56 different parameters related to weaning/extubation outcome.
Highlight: In the validation cohort, the use of ExPreS decreased the extubation failure rate from 8.2% to 2.4%, even in a cohort of more severe patients. It is a simple method and is easily applied at the bedside.
Highlight: COVID-19 patients had an extubation failure risk that was almost three times higher than non-COVID-19 patients, with the extubation of the former being delayed compared to the latter. Furthermore, an age ≥ 66 years, time of symptoms ≥ 31 days, need of dialysis, and PaO2/FiO2 ratio > 200 were independent predictors for extubation failure.
Highlight: Age, molecular subtype, and staging, diabetes was significantly associated with the response to neoadjuvant chemotherapy, highlighting the importance of elucidating the mechanism by which diabetes may impair.
Highlight: this study shows that RSBI has different accuracies depending on the anthropometric specificities of patients and proposes a discussion of its limitations and possible ways to improve its accuracy, especially for patients whose average anthropometric characteristics are not known.
Highlight: A non-invasive, scalable solution that enables real-time ventilator monitoring using only mobile device photos. High performance in detecting PVA, with broad applicability across clinical environments and ventilator types.
Highlight: In this randomized controlled trial, use of the Extubation Predictive Score (ExPreS) was associated with numerically lower rates of reintubation within 48 hours compared with standard care.
Highlight: Double triggering is defined not by the trigger mode of the first breath, but by the neural–ventilatory mismatch underlying breath stacking.
Da evidência à prática
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